School: Medical and Health Sciences

This unit information may be updated and amended immediately prior to semester. To ensure you have the correct outline, please check it again at the beginning of semester.

  • Unit Title

    Advanced Biomedical Techniques
  • Unit Code

    SCH2141
  • Year

    2019
  • Enrolment Period

    1
  • Version

    1
  • Credit Points

    15
  • Full Year Unit

    N
  • Mode of Delivery

    On Campus
  • Unit Coordinator

    Dr Lois Ann BALMER

Description

This unit sets out the basic principles of genomics, proteomics and bioinformatics. The major areas covered are: (i) genome sequences - genomic variation, identity and evolution (ii) genome expression - arrays and proteomics (iii) biomedical genome research - development of vaccines, antibiotics, RNA medicine and genomic ethics (iv) online genomics, proteomics and bioinformatics - a variety of unknown DNAs are isolated, assayed, amplified, sequenced and their sequences analysed using online shareware applications. Instruction employs interesting but complex questions derived from biomedical case studies. Students use bioinformatics to explore the biomedical content and processes contained within each case study.

Prerequisite Rule

Students must pass 1 units from SCH1111, SCH1133, SCH2142

Learning Outcomes

On completion of this unit students should be able to:

  1. Align genomes to identify how evolution has shaped them.
  2. Apply genomic analysis to answer questions about phylogenetic relationships, the origins of life, eukaryotic cells, and the genus Homo.
  3. Compare annotated gene sequences across unicellular and metazoan genomes.
  4. Critique the accuracy, speed and accessibility of microarray technology.
  5. Describe how genetics can be used to understand genomic mechanisms causing disease.
  6. Describe how the genome sequences of pathogens have lead to new treatments.
  7. Explain how genomes are sequenced.
  8. Integrate genomic applications with associated ethical concerns.
  9. Use a range of online shareware applications to communicate with the worldwide bioinformatics community and engage in real-time discoveries.

Unit Content

  1. Entry criteria for biomedical research and diagnostics.
  2. Genomic variation and phylogenetic relationships.
  3. Unicellular and Metazoan genomes.
  4. Probing and applications of DNA microarrays.
  5. Genomic medicine: vaccines, antibiotics, ribozymes and RNA inhibition.
  6. Genome sequence acquisition.
  7. Genome alignment and evolution.
  8. Online shareware applications Chromas Lite, BLAST, Gene ID, BLAT & Genebank.

Additional Learning Experience Information

Lectures with guest lecturers. Laboratory work conducted in pairs or as a whole class. Online genomic and bioinformatic analyses using shareware applications. Guided preparation for Work Integrated Learning. Total contact time is 4 hours per week.

Assessment

GS1 GRADING SCHEMA 1 Used for standard coursework units

Students please note: The marks and grades received by students on assessments may be subject to further moderation. All marks and grades are to be considered provisional until endorsed by the relevant Board of Examiners.

ON CAMPUS
TypeDescriptionValue
TestMid semester test30%
PresentationLaboratory 10 minute talk5%
Laboratory WorkLaboratory reports25%
ExaminationTheory examination40%

Disability Standards for Education (Commonwealth 2005)

For the purposes of considering a request for Reasonable Adjustments under the Disability Standards for Education (Commonwealth 2005), inherent requirements for this subject are articulated in the Unit Description, Learning Outcomes and Assessment Requirements of this entry. The University is dedicated to provide support to those with special requirements. Further details on the support for students with disabilities or medical conditions can be found at the Access and Inclusion website.

Academic Misconduct

Edith Cowan University has firm rules governing academic misconduct and there are substantial penalties that can be applied to students who are found in breach of these rules. Academic misconduct includes, but is not limited to:

  • plagiarism;
  • unauthorised collaboration;
  • cheating in examinations;
  • theft of other students' work;

Additionally, any material submitted for assessment purposes must be work that has not been submitted previously, by any person, for any other unit at ECU or elsewhere.

The ECU rules and policies governing all academic activities, including misconduct, can be accessed through the ECU website.

SCH2141|1|1

School: Medical and Health Sciences

This unit information may be updated and amended immediately prior to semester. To ensure you have the correct outline, please check it again at the beginning of semester.

  • Unit Title

    Advanced Biomedical Techniques
  • Unit Code

    SCH2141
  • Year

    2019
  • Enrolment Period

    2
  • Version

    2
  • Credit Points

    15
  • Full Year Unit

    N
  • Mode of Delivery

    On Campus
  • Unit Coordinator

    Dr Lois Ann BALMER

Description

This unit sets out the basic principles of genomics, proteomics and bioinformatics. The major areas covered are: (i) genome sequences - genomic variation, identity and evolution (ii) genome expression - arrays and proteomics (iii) biomedical genome research - development of vaccines, antibiotics, RNA medicine and genomic ethics (iv) online genomics, proteomics and bioinformatics - a variety of unknown DNAs are isolated, assayed, amplified, sequenced and their sequences analysed using online shareware applications. Instruction employs interesting but complex questions derived from biomedical case studies. Students use bioinformatics to explore the biomedical content and processes contained within each case study.

Prerequisite Rule

Students must have passed SCH1111 or SCH1133.

Learning Outcomes

On completion of this unit students should be able to:

  1. Apply molecular and biochemical theory in the field of genomics.
  2. Communicate knowledge of genomics using correct laboratory terminology.
  3. Analyse the amplicon and characterise the DNA using computational tools.

Unit Content

  1. Theory and application of Genomics, Proteomics and Metabolomics.
  2. Recombinant DNA techniques and molecular cloning.
  3. Application of Flow Cytometry.
  4. Enzymes and Receptors.
  5. Genomic medicine: vaccines, antibiotics, ribozymes and RNA inhibition.
  6. Genome sequence acquisition and fundamentals of Bioinformatics.
  7. Genome alignment and evolution.
  8. Online shareware applications Chromas Lite, BLAST, Gene ID, Genebank, NCBI.

Learning Experience

Students will attend on campus classes as well as engage in learning activities through ECU Blackboard.

JoondalupMount LawleySouth West (Bunbury)
Semester 213 x 2 hour labNot OfferedNot Offered
Semester 213 x 2 hour lectureNot OfferedNot Offered

For more information see the Semester Timetable

Additional Learning Experience Information

Lectures with guest lecturers. Laboratory work conducted in pairs or as a whole class. Online genomic and bioinformatic analyses using shareware applications. Guided preparation for Work Integrated Learning.

Assessment

GS1 GRADING SCHEMA 1 Used for standard coursework units

Students please note: The marks and grades received by students on assessments may be subject to further moderation. All marks and grades are to be considered provisional until endorsed by the relevant Board of Examiners.

ON CAMPUS
TypeDescriptionValue
TestMid semester test25%
PresentationLaboratory 10 minute talk10%
Laboratory WorkLaboratory reports25%
ExaminationTheory examination40%

Disability Standards for Education (Commonwealth 2005)

For the purposes of considering a request for Reasonable Adjustments under the Disability Standards for Education (Commonwealth 2005), inherent requirements for this subject are articulated in the Unit Description, Learning Outcomes and Assessment Requirements of this entry. The University is dedicated to provide support to those with special requirements. Further details on the support for students with disabilities or medical conditions can be found at the Access and Inclusion website.

Academic Misconduct

Edith Cowan University has firm rules governing academic misconduct and there are substantial penalties that can be applied to students who are found in breach of these rules. Academic misconduct includes, but is not limited to:

  • plagiarism;
  • unauthorised collaboration;
  • cheating in examinations;
  • theft of other students' work;

Additionally, any material submitted for assessment purposes must be work that has not been submitted previously, by any person, for any other unit at ECU or elsewhere.

The ECU rules and policies governing all academic activities, including misconduct, can be accessed through the ECU website.

SCH2141|2|2