School: Medical and Health Sciences

This unit information may be updated and amended immediately prior to semester. To ensure you have the correct outline, please check it again at the beginning of semester.

Please note that there may be some modifications to the assessment schedule promoted in Handbook for Semester 1 2023 Units. All assessment changes will be published by 20th February 2023. All students are reminded to check the handbook at the beginning of semester to ensure they have the correct outline.

  • Unit Title

    Human Molecular Genetics
  • Unit Code

    SCH2226
  • Year

    2023
  • Enrolment Period

    1
  • Version

    2
  • Credit Points

    15
  • Full Year Unit

    N
  • Mode of Delivery

    On Campus
  • Unit Coordinator

    Dr Lois Ann BALMER

Description

This unit commences with an analysis of DNA structure, replication and function in prokaryotes and eukaryotes. The mapping and sequencing of the human genome is discussed, followed by consideration of penetrance, expressivity, essential genes, lethal alleles, gene silencing, and genomic imprinting. Focus then switches to gene expression in prokaryotes and eukaryotes before the genetics of cancer integrates central human molecular genetic concepts.

Prerequisite Rule

Students must have passed SCH1133

Equivalent Rule

Unit was previously coded SCH3336

Learning Outcomes

On completion of this unit students should be able to:

  1. Explain how prokaryote and eukaryote molecular mechanisms of DNA replicate into a stepwise temporal sequence of events.
  2. Communicate an advanced understanding of the medical research topic to illustrate broad subject knowledge.
  3. Implement Molecular Biology techniques in collaboration with a group project so as to understand positional cloning and sequencing.

Unit Content

  1. The genetic material and DNA Replication.
  2. Extensions of Mendelian genetic principles.
  3. Mapping and sequencing the human genome: The Human Genome Diversity Panel: Worldwide Human Relationships.
  4. Transcription, translation and the regulation of gene expression in bacteria.
  5. Regulation of gene expression in eukaryotes.
  6. Mapping bacterial genomes.
  7. Expression vector cloning of human gene exons.
  8. Genetics of cancer.

Learning Experience

Students will attend on campus classes as well as engage in learning activities through ECU's LMS

JoondalupMount LawleySouth West (Bunbury)
Semester 113 x 2 hour labNot OfferedNot Offered
Semester 113 x 2 hour lectureNot OfferedNot Offered

For more information see the Semester Timetable

Additional Learning Experience Information

Lectures incorporate key questions designed to prime students for major concepts, and summaries of major ideas and critical points. Sporadically guest speakers will be invited that highlight student opportunities for future employment. The use of digital technology engages students in their development of academic writing and provides real world readiness. In the laboratory, students work in pairs to conduct experiments and critically analyse their findings. Each week, one group of students presents a review of laboratory progress to the rest of the class, developing self-management and responsibility capabilities.

Assessment

GS1 GRADING SCHEMA 1 Used for standard coursework units

Students please note: The marks and grades received by students on assessments may be subject to further moderation. All marks and grades are to be considered provisional until endorsed by the relevant School Progression Panel.

ON CAMPUS
TypeDescriptionValue
TestMid semester test25%
Laboratory WorkLaboratory reports and presentation25%
Laboratory Work ^Practical test25%
ExaminationSemester examination25%

^ Mandatory to Pass


Disability Standards for Education (Commonwealth 2005)

For the purposes of considering a request for Reasonable Adjustments under the Disability Standards for Education (Commonwealth 2005), inherent requirements for this subject are articulated in the Unit Description, Learning Outcomes and Assessment Requirements of this entry. The University is dedicated to provide support to those with special requirements. Further details on the support for students with disabilities or medical conditions can be found at the Access and Inclusion website.

Assessment

Students please note: The marks and grades received by students on assessments may be subject to further moderation. Informal vivas may be conducted as part of an assessment task, where staff require further information to confirm the learning outcomes have been met. All marks and grades are to be considered provisional until endorsed by the relevant School Progression Panel.

Academic Integrity

Integrity is a core value at Edith Cowan University, and it is expected that ECU students complete their assessment tasks honestly and with acknowledgement of other people's work as well as any generative artificial intelligence tools that may have been used. This means that assessment tasks must be completed individually (unless it is an authorised group assessment task) and any sources used must be referenced.

Breaches of academic integrity can include:

Plagiarism

Copying the words, ideas or creative works of other people or generative artificial intelligence tools, without referencing in accordance with stated University requirements. Students need to seek approval from the Unit Coordinator within the first week of study if they intend to use some of their previous work in an assessment task (self-plagiarism).

Unauthorised collaboration (collusion)

Working with other students and submitting the same or substantially similar work or portions of work when an individual submission was required. This includes students knowingly providing others with copies of their own work to use in the same or similar assessment task(s).

Contract cheating

Organising a friend, a family member, another student or an external person or organisation (e.g. through an online website) to complete or substantially edit or refine part or all of an assessment task(s) on their behalf.

Cheating in an exam

Using or having access to unauthorised materials in an exam or test.

Serious outcomes may be imposed if a student is found to have committed one of these breaches, up to and including expulsion from the University for repeated or serious acts.

ECU's policies and more information about academic integrity can be found on the student academic integrity website.

All commencing ECU students are required to complete the Academic Integrity Module.

Assessment Extension

In some circumstances, Students may apply to their Unit Coordinator to extend the due date of their Assessment Task(s) in accordance with ECU's Assessment, Examination and Moderation Procedures - for more information visit https://askus2.ecu.edu.au/s/article/000001386.

Special Consideration

Students may apply for Special Consideration in respect of a final unit grade, where their achievement was affected by Exceptional Circumstances as set out in the Assessment, Examination and Moderation Procedures - for more information visit https://askus2.ecu.edu.au/s/article/000003318.

SCH2226|2|1

School: Medical and Health Sciences

This unit information may be updated and amended immediately prior to semester. To ensure you have the correct outline, please check it again at the beginning of semester.

  • Unit Title

    Human Molecular Genetics
  • Unit Code

    SCH2226
  • Year

    2023
  • Enrolment Period

    2
  • Version

    2
  • Credit Points

    15
  • Full Year Unit

    N
  • Mode of Delivery

    On Campus
  • Unit Coordinator

    Dr Lois Ann BALMER

Description

This unit commences with an analysis of DNA structure, replication and function in prokaryotes and eukaryotes. The mapping and sequencing of the human genome is discussed, followed by consideration of penetrance, expressivity, essential genes, lethal alleles, gene silencing, and genomic imprinting. Focus then switches to gene expression in prokaryotes and eukaryotes before the genetics of cancer integrates central human molecular genetic concepts.

Prerequisite Rule

Students must have passed SCH1133

Equivalent Rule

Unit was previously coded SCH3336

Learning Outcomes

On completion of this unit students should be able to:

  1. Explain how prokaryote and eukaryote molecular mechanisms of DNA replicate into a stepwise temporal sequence of events.
  2. Communicate an advanced understanding of the medical research topic to illustrate broad subject knowledge.
  3. Implement Molecular Biology techniques in collaboration with a group project so as to understand positional cloning and sequencing.

Unit Content

  1. The genetic material and DNA Replication.
  2. Extensions of Mendelian genetic principles.
  3. Mapping and sequencing the human genome: The Human Genome Diversity Panel: Worldwide Human Relationships.
  4. Transcription, translation and the regulation of gene expression in bacteria.
  5. Regulation of gene expression in eukaryotes.
  6. Mapping bacterial genomes.
  7. Expression vector cloning of human gene exons.
  8. Genetics of cancer.

Learning Experience

Students will attend on campus classes as well as engage in learning activities through ECU's LMS

JoondalupMount LawleySouth West (Bunbury)
Semester 113 x 2 hour labNot OfferedNot Offered
Semester 113 x 2 hour lectureNot OfferedNot Offered

For more information see the Semester Timetable

Additional Learning Experience Information

Lectures incorporate key questions designed to prime students for major concepts, and summaries of major ideas and critical points. Sporadically guest speakers will be invited that highlight student opportunities for future employment. The use of digital technology engages students in their development of academic writing and provides real world readiness. In the laboratory, students work in pairs to conduct experiments and critically analyse their findings. Each week, one group of students presents a review of laboratory progress to the rest of the class, developing self-management and responsibility capabilities.

Assessment

GS1 GRADING SCHEMA 1 Used for standard coursework units

Students please note: The marks and grades received by students on assessments may be subject to further moderation. All marks and grades are to be considered provisional until endorsed by the relevant School Progression Panel.

ON CAMPUS
TypeDescriptionValue
TestMid semester test25%
Laboratory WorkLaboratory reports and presentation25%
Laboratory Work ^Practical test25%
ExaminationSemester examination25%

^ Mandatory to Pass


Disability Standards for Education (Commonwealth 2005)

For the purposes of considering a request for Reasonable Adjustments under the Disability Standards for Education (Commonwealth 2005), inherent requirements for this subject are articulated in the Unit Description, Learning Outcomes and Assessment Requirements of this entry. The University is dedicated to provide support to those with special requirements. Further details on the support for students with disabilities or medical conditions can be found at the Access and Inclusion website.

Assessment

Students please note: The marks and grades received by students on assessments may be subject to further moderation. Informal vivas may be conducted as part of an assessment task, where staff require further information to confirm the learning outcomes have been met. All marks and grades are to be considered provisional until endorsed by the relevant School Progression Panel.

Academic Integrity

Integrity is a core value at Edith Cowan University, and it is expected that ECU students complete their assessment tasks honestly and with acknowledgement of other people's work as well as any generative artificial intelligence tools that may have been used. This means that assessment tasks must be completed individually (unless it is an authorised group assessment task) and any sources used must be referenced.

Breaches of academic integrity can include:

Plagiarism

Copying the words, ideas or creative works of other people or generative artificial intelligence tools, without referencing in accordance with stated University requirements. Students need to seek approval from the Unit Coordinator within the first week of study if they intend to use some of their previous work in an assessment task (self-plagiarism).

Unauthorised collaboration (collusion)

Working with other students and submitting the same or substantially similar work or portions of work when an individual submission was required. This includes students knowingly providing others with copies of their own work to use in the same or similar assessment task(s).

Contract cheating

Organising a friend, a family member, another student or an external person or organisation (e.g. through an online website) to complete or substantially edit or refine part or all of an assessment task(s) on their behalf.

Cheating in an exam

Using or having access to unauthorised materials in an exam or test.

Serious outcomes may be imposed if a student is found to have committed one of these breaches, up to and including expulsion from the University for repeated or serious acts.

ECU's policies and more information about academic integrity can be found on the student academic integrity website.

All commencing ECU students are required to complete the Academic Integrity Module.

Assessment Extension

In some circumstances, Students may apply to their Unit Coordinator to extend the due date of their Assessment Task(s) in accordance with ECU's Assessment, Examination and Moderation Procedures - for more information visit https://askus2.ecu.edu.au/s/article/000001386.

Special Consideration

Students may apply for Special Consideration in respect of a final unit grade, where their achievement was affected by Exceptional Circumstances as set out in the Assessment, Examination and Moderation Procedures - for more information visit https://askus2.ecu.edu.au/s/article/000003318.

SCH2226|2|2