Faculty of Health, Engineering and Science

School: Medical Sciences

This unit information may be updated and amended immediately prior to semester. To ensure you have the correct outline, please check it again at the beginning of semester.

  • Unit Title

    Advances in Human Biology 1
  • Unit Code

    SCH5105
  • Year

    2015
  • Enrolment Period

    1
  • Version

    1
  • Credit Points

    20
  • Full Year Unit

    N
  • Mode of Delivery

    On Campus

Description

This unit will contain a selection of topics from the history and philosophy of science, human molecular biology, and cardiac and skeletal muscle physiology. The unit will be supplemented by visiting lecturers and research fellows as appropriate.

Learning Outcomes

On completion of this unit students should be able to:

  1. Demonstrate an understanding of the development of science from historical and philosophical perspectives.
  2. Describe major advancements in skeletal and cardiac muscle physiological research.
  3. Explain and evaluate investigative physiological methodologies available for skeletal and cardiac muscle research in the myothermic, contractile, enzymatic and histological fields.
  4. Explain and evaluate selected gene mapping techniques.
  5. Explain the molecular nature of defects that cause the haemoglobinopathies.

Unit Content

  1. Cardiac and Skeletal Muscle Physiology - Myothermic techniques and their development; the monitoring of muscle metabolism, calcium fluxes during muscular contraction, muscular contraction (from whole muscles to single fibres). Chemical and mechanical skinning of muscle fibres to investigate contractile dynamics; muscle fibre type and classification using contractile and enzymatic criteria; contractile protein structure; histological staining of fibre types specific to myosin ATPase activity. Muscular contraction: energetic cost (resting, activation, maintenance and recovery heats), visco-elastic theory of muscular contraction and compartmentalisation of the energy flux of contraction, computer models, muscular efficiency. The pathophysiology of common myopathies.
  2. Human Molecular Biology Principles underlying the biochemistry and molecular genetics of human disease with special emphasis on the haemoglobinopathies. The anatomy of the human genome as revealed by molecular mapping techniques and linkage analysis. The molecular biology of cancer.
  3. The History and Philosophy of Science. The History of Science: Attention will be focussed on the development of crucial elements of the modern science disciplines. Possible topics for discussion include; The Copernican System, The Theory of Universal Gravitation, The Circulatory System, The Structure and Function of Living Organisms, Cell Theory, The Development of Genetics, The Development of Evolutionary Theory, Chemistry and the Atomic Theory. The Philosophy of Science: This topic addresses the evolution of the scientific process. The following topics may be investigated; Francis Bacon and the inductive method, Karl Popper - conjectures and falsifications, Thomas Kuhn and scientific revolutions.

Additional Learning Experience Information

Lectures, seminars, directed reading.

Assessment

GS4 GRADING SCHEMA 4 Used for undifferentiated pass/fail units

Students please note: The marks and grades received by students on assessments may be subject to further moderation. All marks and grades are to be considered provisional until endorsed by the relevant Board of Examiners.

ON CAMPUS
TypeDescription
ParticipationSeminar
ExaminationExamination

Text References

  • Birch, C., & Cobb J.B. (1984). The liberation of life. Cambridge London: Cambridge University Press.
  • Charlesworth, M. (1982). Science, non-science and pseudo-science. Victoria: Deakin University Press.
  • Ganong, A.C. (1989). Textbook of medical physiology (7th ed.). Tokyo: Igaku-Saunders.
  • Gelehrter, T.D. & Collins, F.S. (1990). Principles of medical genetics. Sydney: Williams and Williams.
  • Hill, A.V. (1965). Trails and trials in physiology. London: Edward Arnold.
  • Micklos, D.A. & Fryer, G.A. (1990). DNA science: A first course in recombinant DNA technology. USA: Cold Spring Harbour Laboratory Press.
  • Sheldrake, R. (1990). The rebirth of nature. London: Century.

Journal References

  • American Journal of Genetics
  • Science
  • American Journal of Physiology
  • Annual Review of Physiology
  • Journal of Human Genetics
  • Journal of Molecular Biology
  • Journal of Physiology
  • Muscle and Nerve
  • Nature
  • News in Physiological Sciences

Other References

  • Woledge, R. A model of muscular contraction. London: University College. Note: COMPUTER SOFTWARE.

Disability Standards for Education (Commonwealth 2005)

For the purposes of considering a request for Reasonable Adjustments under the Disability Standards for Education (Commonwealth 2005), inherent requirements for this subject are articulated in the Unit Description, Learning Outcomes and Assessment Requirements of this entry. The University is dedicated to provide support to those with special requirements. Further details on the support for students with disabilities or medical conditions can be found at the Access and Inclusion website.

Academic Misconduct

Edith Cowan University has firm rules governing academic misconduct and there are substantial penalties that can be applied to students who are found in breach of these rules. Academic misconduct includes, but is not limited to:

  • plagiarism;
  • unauthorised collaboration;
  • cheating in examinations;
  • theft of other students' work;

Additionally, any material submitted for assessment purposes must be work that has not been submitted previously, by any person, for any other unit at ECU or elsewhere.

The ECU rules and policies governing all academic activities, including misconduct, can be accessed through the ECU website.

SCH5105|1|1

Faculty of Health, Engineering and Science

School: Medical Sciences

This unit information may be updated and amended immediately prior to semester. To ensure you have the correct outline, please check it again at the beginning of semester.

  • Unit Title

    Advances in Human Biology 1
  • Unit Code

    SCH5105
  • Year

    2015
  • Enrolment Period

    2
  • Version

    1
  • Credit Points

    20
  • Full Year Unit

    N
  • Mode of Delivery

    On Campus

Description

This unit will contain a selection of topics from the history and philosophy of science, human molecular biology, and cardiac and skeletal muscle physiology. The unit will be supplemented by visiting lecturers and research fellows as appropriate.

Learning Outcomes

On completion of this unit students should be able to:

  1. Demonstrate an understanding of the development of science from historical and philosophical perspectives.
  2. Describe major advancements in skeletal and cardiac muscle physiological research.
  3. Explain and evaluate investigative physiological methodologies available for skeletal and cardiac muscle research in the myothermic, contractile, enzymatic and histological fields.
  4. Explain and evaluate selected gene mapping techniques.
  5. Explain the molecular nature of defects that cause the haemoglobinopathies.

Unit Content

  1. Cardiac and Skeletal Muscle Physiology - Myothermic techniques and their development; the monitoring of muscle metabolism, calcium fluxes during muscular contraction, muscular contraction (from whole muscles to single fibres). Chemical and mechanical skinning of muscle fibres to investigate contractile dynamics; muscle fibre type and classification using contractile and enzymatic criteria; contractile protein structure; histological staining of fibre types specific to myosin ATPase activity. Muscular contraction: energetic cost (resting, activation, maintenance and recovery heats), visco-elastic theory of muscular contraction and compartmentalisation of the energy flux of contraction, computer models, muscular efficiency. The pathophysiology of common myopathies.
  2. Human Molecular Biology Principles underlying the biochemistry and molecular genetics of human disease with special emphasis on the haemoglobinopathies. The anatomy of the human genome as revealed by molecular mapping techniques and linkage analysis. The molecular biology of cancer.
  3. The History and Philosophy of Science. The History of Science: Attention will be focussed on the development of crucial elements of the modern science disciplines. Possible topics for discussion include; The Copernican System, The Theory of Universal Gravitation, The Circulatory System, The Structure and Function of Living Organisms, Cell Theory, The Development of Genetics, The Development of Evolutionary Theory, Chemistry and the Atomic Theory. The Philosophy of Science: This topic addresses the evolution of the scientific process. The following topics may be investigated; Francis Bacon and the inductive method, Karl Popper - conjectures and falsifications, Thomas Kuhn and scientific revolutions.

Additional Learning Experience Information

Lectures, seminars, directed reading.

Assessment

GS4 GRADING SCHEMA 4 Used for undifferentiated pass/fail units

Students please note: The marks and grades received by students on assessments may be subject to further moderation. All marks and grades are to be considered provisional until endorsed by the relevant Board of Examiners.

ON CAMPUS
TypeDescription
ParticipationSeminar
ExaminationExamination

Text References

  • Birch, C., & Cobb J.B. (1984). The liberation of life. Cambridge London: Cambridge University Press.
  • Charlesworth, M. (1982). Science, non-science and pseudo-science. Victoria: Deakin University Press.
  • Ganong, A.C. (1989). Textbook of medical physiology (7th ed.). Tokyo: Igaku-Saunders.
  • Gelehrter, T.D. & Collins, F.S. (1990). Principles of medical genetics. Sydney: Williams and Williams.
  • Hill, A.V. (1965). Trails and trials in physiology. London: Edward Arnold.
  • Micklos, D.A. & Fryer, G.A. (1990). DNA science: A first course in recombinant DNA technology. USA: Cold Spring Harbour Laboratory Press.
  • Sheldrake, R. (1990). The rebirth of nature. London: Century.

Journal References

  • American Journal of Genetics
  • Science
  • American Journal of Physiology
  • Annual Review of Physiology
  • Journal of Human Genetics
  • Journal of Molecular Biology
  • Journal of Physiology
  • Muscle and Nerve
  • Nature
  • News in Physiological Sciences

Other References

  • Woledge, R. A model of muscular contraction. London: University College. Note: COMPUTER SOFTWARE.

Disability Standards for Education (Commonwealth 2005)

For the purposes of considering a request for Reasonable Adjustments under the Disability Standards for Education (Commonwealth 2005), inherent requirements for this subject are articulated in the Unit Description, Learning Outcomes and Assessment Requirements of this entry. The University is dedicated to provide support to those with special requirements. Further details on the support for students with disabilities or medical conditions can be found at the Access and Inclusion website.

Academic Misconduct

Edith Cowan University has firm rules governing academic misconduct and there are substantial penalties that can be applied to students who are found in breach of these rules. Academic misconduct includes, but is not limited to:

  • plagiarism;
  • unauthorised collaboration;
  • cheating in examinations;
  • theft of other students' work;

Additionally, any material submitted for assessment purposes must be work that has not been submitted previously, by any person, for any other unit at ECU or elsewhere.

The ECU rules and policies governing all academic activities, including misconduct, can be accessed through the ECU website.

SCH5105|1|2