School: Science

This unit information may be updated and amended immediately prior to semester. To ensure you have the correct outline, please check it again at the beginning of semester.

  • Unit Title

    Mass Spectrometry in Systems Biology
  • Unit Code

    SCI6152
  • Year

    2021
  • Enrolment Period

    1
  • Version

    1
  • Credit Points

    20
  • Full Year Unit

    N
  • Mode of Delivery

    On Campus
    Online
  • Unit Coordinator

    Dr Stacey Nichole REINKE

Description

This unit introduces students to the application of high-resolution mass spectrometry to the systems biology fields of proteomics and metabolomics. High-resolution mass spectrometry is state-of-the-art instrumentation that is commonly used in research laboratories to comprehensively profile peptides and metabolites in biological systems. This unit covers the theory and utility of high-resolution mass spectrometry as well as the data processing workflow used to extract information from raw spectral files and convert it into a data matrix used for subsequent data analysis.

Learning Outcomes

On completion of this unit students should be able to:

  1. Apply the theory of high-resolution mass spectrometry in the context of proteomics and metabolomics.
  2. Critically assess methods and guidelines for mass spectral standard operating procedures, data pre-processing, feature identification, and quality assessment, as they relate to proteomics and metabolomics.
  3. Pre-process mass spectral data, optimise settings for pre-processing, perform feature identification, and assess resulting data quality.
  4. Defend decisions for choice of pre-processing approach, feature identification, and data cleaning.

Unit Content

  1. Introduction to proteomics and metabolomics as fields of systems biology.
  2. Theory of high-resolution mass spectrometry as it relates to proteomics and metabolomics.
  3. Spectral pre-processing.
  4. Feature identification.
  5. Quality assurance, quality control, and reporting.

Learning Experience

ON-CAMPUS

Students will attend on campus classes as well as engage in learning activities through ECUs LMS

JoondalupMount LawleySouth West (Bunbury)
Semester 213 x 3 hour workshopNot OfferedNot Offered

For more information see the Semester Timetable

ONLINE

Students will engage in learning experiences through ECUs LMS as well as additional ECU l

Additional Learning Experience Information

Students will work closely with staff in an industry-sponsored laboratory setting to gain first-hand experience of the theory and utility of high-resolution mass spectrometry and associated data processing workflows.

Assessment

GS1 GRADING SCHEMA 1 Used for standard coursework units

Students please note: The marks and grades received by students on assessments may be subject to further moderation. All marks and grades are to be considered provisional until endorsed by the relevant School Progression Panel.

ON CAMPUS
TypeDescriptionValue
PortfolioProteomics Portfolio40%
PortfolioMetabolomics Portfolio40%
PresentationOral Presentation20%
ONLINE
TypeDescriptionValue
PortfolioProteomics Portfolio40%
PortfolioMetabolomics Portfolio40%
PresentationOral Presentation20%

Disability Standards for Education (Commonwealth 2005)

For the purposes of considering a request for Reasonable Adjustments under the Disability Standards for Education (Commonwealth 2005), inherent requirements for this subject are articulated in the Unit Description, Learning Outcomes and Assessment Requirements of this entry. The University is dedicated to provide support to those with special requirements. Further details on the support for students with disabilities or medical conditions can be found at the Access and Inclusion website.

Academic Misconduct

Edith Cowan University has firm rules governing academic misconduct and there are substantial penalties that can be applied to students who are found in breach of these rules. Academic misconduct includes, but is not limited to:

  • plagiarism;
  • unauthorised collaboration;
  • cheating in examinations;
  • theft of other students' work;

Additionally, any material submitted for assessment purposes must be work that has not been submitted previously, by any person, for any other unit at ECU or elsewhere.

The ECU rules and policies governing all academic activities, including misconduct, can be accessed through the ECU website.

SCI6152|1|1

School: Science

This unit information may be updated and amended immediately prior to semester. To ensure you have the correct outline, please check it again at the beginning of semester.

  • Unit Title

    Mass Spectrometry in Systems Biology
  • Unit Code

    SCI6152
  • Year

    2021
  • Enrolment Period

    2
  • Version

    1
  • Credit Points

    20
  • Full Year Unit

    N
  • Mode of Delivery

    On Campus
    Online
  • Unit Coordinator

    Dr Stacey Nichole REINKE

Description

This unit introduces students to the application of high-resolution mass spectrometry to the systems biology fields of proteomics and metabolomics. High-resolution mass spectrometry is state-of-the-art instrumentation that is commonly used in research laboratories to comprehensively profile peptides and metabolites in biological systems. This unit covers the theory and utility of high-resolution mass spectrometry as well as the data processing workflow used to extract information from raw spectral files and convert it into a data matrix used for subsequent data analysis.

Learning Outcomes

On completion of this unit students should be able to:

  1. Apply the theory of high-resolution mass spectrometry in the context of proteomics and metabolomics.
  2. Critically assess methods and guidelines for mass spectral standard operating procedures, data pre-processing, feature identification, and quality assessment, as they relate to proteomics and metabolomics.
  3. Pre-process mass spectral data, optimise settings for pre-processing, perform feature identification, and assess resulting data quality.
  4. Defend decisions for choice of pre-processing approach, feature identification, and data cleaning.

Unit Content

  1. Introduction to proteomics and metabolomics as fields of systems biology.
  2. Theory of high-resolution mass spectrometry as it relates to proteomics and metabolomics.
  3. Spectral pre-processing.
  4. Feature identification.
  5. Quality assurance, quality control, and reporting.

Learning Experience

ON-CAMPUS

Students will attend on campus classes as well as engage in learning activities through ECUs LMS

JoondalupMount LawleySouth West (Bunbury)
Semester 213 x 3 hour workshopNot OfferedNot Offered

For more information see the Semester Timetable

ONLINE

Students will engage in learning experiences through ECUs LMS as well as additional ECU l

Additional Learning Experience Information

Students will work closely with staff in an industry-sponsored laboratory setting to gain first-hand experience of the theory and utility of high-resolution mass spectrometry and associated data processing workflows.

Assessment

GS1 GRADING SCHEMA 1 Used for standard coursework units

Students please note: The marks and grades received by students on assessments may be subject to further moderation. All marks and grades are to be considered provisional until endorsed by the relevant School Progression Panel.

ON CAMPUS
TypeDescriptionValue
PortfolioProteomics Portfolio40%
PortfolioMetabolomics Portfolio40%
PresentationOral Presentation20%
ONLINE
TypeDescriptionValue
PortfolioProteomics Portfolio40%
PortfolioMetabolomics Portfolio40%
PresentationOral Presentation20%

Disability Standards for Education (Commonwealth 2005)

For the purposes of considering a request for Reasonable Adjustments under the Disability Standards for Education (Commonwealth 2005), inherent requirements for this subject are articulated in the Unit Description, Learning Outcomes and Assessment Requirements of this entry. The University is dedicated to provide support to those with special requirements. Further details on the support for students with disabilities or medical conditions can be found at the Access and Inclusion website.

Academic Misconduct

Edith Cowan University has firm rules governing academic misconduct and there are substantial penalties that can be applied to students who are found in breach of these rules. Academic misconduct includes, but is not limited to:

  • plagiarism;
  • unauthorised collaboration;
  • cheating in examinations;
  • theft of other students' work;

Additionally, any material submitted for assessment purposes must be work that has not been submitted previously, by any person, for any other unit at ECU or elsewhere.

The ECU rules and policies governing all academic activities, including misconduct, can be accessed through the ECU website.

SCI6152|1|2