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    Pengxiang Ying

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Bovine arch and risk of aortic-related adverse events following TEVAR in type B aortic dissection: Evidence from a clinical cohort and computational fluid dynamics

Student name:

Pengxiang Ying (PhD candidate)

Supervisors:

  1. Professor Wei Wang
  2. Professor Xuerui Tan
  3. Dr Lois Balmer
  4. Dr Xingang Li
  5. Dr Manshu Song

Summary of thesis:

The management of type B aortic dissection (TBAD) after thoracic endovascular aortic repair (TEVAR) is challenging due to the risk of
aortic-related adverse events (ARAE). Given that peculiar geometric pattern of proximal landing zone and hemodynamic features in bovine arch, we hypothesis that bovine arch may be associated with ARAE after TEVAR in TBAD from a clinical perspective. This study first validated the association through a retrospective multicentre cohort study. Furthermore, it provided potential hemodynamic mechanisms underlying this association using computational fluid dynamics analysis. The findings may offer clinicians easily identifiable markers for risk stratification, improving outcomes of this high-risk population.

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