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Proteomics Facility

Modern analytical chemistry instrumentation supports world class proteomics research at ECU. The proteomics laboratory group is well-equipped with two complementary liquid chromatography-mass spectrometry platforms that enable the discovery and quantitation of proteins in complex samples. Our high-resolution accurate mass QTOF instrument is coupled with a nanoLC system and integrates comprehensive qualitative exploration, rapid profiling, and high-resolution quantitation of low-abundance analytes in very complex matrices. When quantifying trace amounts of analyte, our triple quadrupole LC-MS system offers multiple reaction monitoring experiments that offer lower limits of detection at higher throughputs. We specialise in food and agricultural proteomics and have ongoing projects investigating allergens and nutritional proteins in cereal grains, the physiology of lupin and related legumes, and bioactive peptides in milk and other functional food matrices.

List of equipment

  • Eksigent nanoLC425 liquid chromatography system
  • AB Sciex 6600 TripleTOF mass spectrometer
  • Exion liquid chromatography system
  • QTRAP 6500+ mass spectrometer
  • Varioscan LUX multimode microplate reader
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