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    Dr Hayley Abbiss - Vice Chancellor's Research Fellow

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Dr Hayley Abbiss

Lecturer

Staff Member Details
Telephone: +61 8 6304 5955
Email: h.abbiss@ecu.edu.au
Campus: Joondalup  
Room: JO19.364  
ORCID iD: https://orcid.org/0000-0002-6821-5564

Overview of role

Hayley is a Vice Chancellor’s Research Fellow in the Centre for Integrative Metabolomics and Computational Biology (CIMCB) in the School of Science.

Current Teaching

  • SCC1126 Introduction to Organic Chemistry and Biochemistry
  • SCC2211 Organic Chemistry
  • SCC3201 Analytical Chemistry

Background

Hayley is an early career researcher experienced in analytical chemistry and metabolomics, in particular, the use of gas and liquid chromatography-mass spectrometry techniques for profiling small molecules in complex samples. To date the majority of this work has been in biochemistry, exploring human and animal samples for small molecule biomarkers of diseases such as asthma, otitis media and polycystic kidney disease. Hayley has also used these metabolomics approaches in agriculture and food systems to uncover biochemical mechanisms underlying grain quality.

Professional Memberships

  • 2019 - Australia and New Zealand Metabolomics Network (Member)
  • 2017 - Metabolomics Australia Bioinformatics Working Group (Member)
  • 2016 - Western Australian Mass Spectrometry Discussion Group (Member)
  • 2015 - Metabolomics Society (Member)
  • 2012 - American Society for Mass Spectrometry (Member)
  • 2010 - Australian and New Zealand Society for Mass Spectrometry (Member)
  • 2010 - Royal Australian Chemical Institute (Member)

Awards and Recognition

  • 2012 - Poster prize for the ‘Omics’ discipline at the 22nd annual Combined Biological Sciences Meeting, Perth, WA
  • 2011 - Poster prize for the RACI synthetic and organic group virtual poster competition, Perth, WA
  • 2009 - Dean’s List, Edith Cowan University, Perth, WA

Research Areas and Interests

  • Chromatography
  • Mass Spectrometry
  • Metabolomics

Qualifications

  • Doctor of Philosophy, Murdoch University, 2018.
  • Bachelor of Science majoring in Env Science & Appplied Chemi, Edith Cowan University, 2009.

Research Outputs

2024

Journal Articles

  • Abbiss, H., Shafaei Darestani, A., Bannister, M., Boyce, M. (2024). Quantitative Determination of Short Chain Fatty Acids in Synthetic Feces Using Gas Chromatography with Flame Ionization Detection or Mass Spectrometry. Journal of Chemical Education, 101(1), 113-119. https://doi.org/10.1021/acs.jchemed.3c00340.

2022

Journal Articles

  • Shafaei Darestani, A., Abbiss, H., Coutts, S., Bannister, M., Bruemmer, J., Boyce, M. (2022). Tocopherols in Seeds and Nuts: QuEChERS Extraction, HPLC Separation, and Fluorescence Detection. Journal of Chemical Education, 99(5), 2093-2100. https://doi.org/10.1021/acs.jchemed.1c01203.

2020

Journal Articles

  • Abbiss, H., Gummer, J., Francki, M., Trengove, RD. (2020). Untargeted liquid chromatography-mass spectrometry-based metabolomics analysis of wheat grain. Journal of Visualized Experiments, March 2020(157), Article number e60851. https://doi.org/10.3791/60851.

2019

Journal Articles

  • Abbiss, H., Maker, GL., Trengove, RD. (2019). Metabolomics approaches for the diagnosis and understanding of kidney diseases. Metabolites, 9(2), Article number 34. https://doi.org/10.3390/metabo9020034.
  • Abbiss, H., Maker, GL., Gummer, J., Rawlinson, C., Musk, GC., Fleming, PA., Phillips, JK., Boyce, M., Trengove, RD. (2019). Untargeted gas chromatography–mass spectrometry-based metabolomics analysis of kidney and liver tissue from the Lewis Polycystic Kidney rat. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1118-1119(15 June 2019), 25-32. https://doi.org/10.1016/j.jchromb.2019.04.021.

2015

Journal Articles

  • Abbiss, H., Rawlinson, C., Maker, GL., Trengove, R. (2015). Assessment of automated trimethylsilyl derivatization protocols for GC–MS-based untargeted metabolomic analysis of urine. Metabolomics, 11(6), 1908-1921. https://doi.org/10.1007/s11306-015-0839-y.

2012

Journal Articles

  • Abbiss, H., Maker, GL., Gummer, J., Sharman, M., Phillips, JK., Boyce, M., Trengove, RD. (2012). Development of a non-targeted metabolomics method to investigate urine in a rat model of polycystic kidney disease. Nephrology, 17(2), 104-110. https://doi.org/10.1111/j.1440-1797.2011.01532.x.

Research Projects

  • Creating a new Forensic Capability in WA by using the Human Hair Shaft Proteome for Protein-based Human Identification., Western Australian Treasury Corporation, Grant, 2024 ‑ 2028, $232,000.
  • Development of a Routine Forensic Process for Individual Identification using Genetically Variant Peptides in Human Hair Evidence , Chemistry Centre WA T/A ChemCentre, Top Up Scholarship, 2022 ‑ 2026, $52,500.
  • Exploring the health effects of S-methyl cysteine sulfoxide for the prevention of type 2 diabetes, Edith Cowan University, Early-Mid Career Researcher Grant Scheme 2022 (Stream 2), 2023 ‑ 2024, $39,511.
  • Sponsorship Agreement for Research Fellow in Analytical Chemistry/Proteomics, Chemistry Centre WA T/A ChemCentre, Research Fellowship Grant, 2017 ‑ 2023, $701,666.
  • Influence of Enzyme Rich Malt Extract on gut health symptoms of irritable bowel syndrome and endurance exercise performance, Ateria Health Australia Pty Ltd, Grant, 2020 ‑ 2023, $534,799.

Research Student Supervision

Current Supervisions

Principal Supervisor

  • Doctor of Philosophy, Development of a Routine Forensic Process for Individual Identification using Genetically Variant Peptides in Human Hair Evidence
  • Master of Science by Research, Development of a GC-MS Method to Extract and Quantify Gamma Hydroxybutyrate from Hair to Assist Forensic Investigation
  • Doctor of Philosophy, Investigation of metabolite biomarkers for early, minimally invasive detection of polycystic kidney disease.

Co-principal Supervisor

  • Master of Science by Research, Development and validation of a liquid chromatography-tandem mass spectrometry method for the identification and quantification of an array of bile acids in human plasma samples to better understand irritable bowel syndrome

Associate Supervisor

  • Doctor of Philosophy, Multi-omics driven engineering of an extremophile for enhanced bioleaching and production of high value bioproducts and biocatalysts
  • Doctor of Philosophy, Characterisation of genetically variant proteins using high-resolution mass spectrometry for taxonomic assignment of biological evidence in the forensic setting

Completed Supervisions

Principal Supervisor

  • Master of Science by Research, Comparison of Tissue Extraction Methods for Gas Chromatography-Mass Spectrometry-Based Metabolomics Analysis of Polycystic Kidney Tissue
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